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The Deadly Influence of Formula in America

By Linda Folden Palmer, DC
Author of Baby Matters

We would like to thank Dr. Palmer for writing this excellent article and for giving us permission to reproduce it on our website for our readers. If you or anyone you know is pregnant or nursing we highly encourage you to read Dr. Palmer’s book Baby Matters. It is full of excellent information on taking care of your baby. You can find it at her website: babyreference.com

A study published in the journal Pediatrics, (May 2004), titled "Breastfeeding and the Risk of Postneonatal Death in the United States," reports a 21% reduction in infant death for having EVER breastfed.

When they compare 3 months of any breastfeeding to less or no breastfeeding, the reported reduction is 36%. That's 36% fewer infant deaths! If they were to compare 3 months of exclusive breastfeeding to no breastmilk, their number would have been closer to 50% the same number as in my prior research article BELOW:

(ADDED April 2006): This study and my below article are about industrialized nations. A more-recent large-scale study taking place in poor areas of Ghana, India, and Peru found a shocking 10.5 times the number of deaths for those not breastfed versus those exclusively breastfed. Partially breastfed infants had 2.5 times the risk of death as those exclusively breastfed. Bulletin of the World Health Organization, 2005

February 1, 2004
Infant formula was designed to be a medical nutritional tool for babies who are unable to breastfeed. Formula does not fully meet the nutritional and immunity needs of infants, leaving their tiny systems flailing. An infant's immune system has three aspects: her own immature, developing immune system; the small component of immunities that passes through the placenta during natural childbirth (and to a lesser degree with premature births and cesarean sections); and the most vast and valuable, living portion that is passed on through mother's milk on an ongoing basis. Remove any of these components and you take away a vital support structure.

This brings us face to face with the safety and effectiveness of infant formula as a breast milk substitute. Is formula actually as safe as we have been led to believe? In fact, the answer is a resounding "no." In fact, the use of infant formula doubles the risk of infant death for American babies.

While the dangers of formula feeding aren't something you're likely to hear in your doctor's office, the conclusions can be derived through an examination of the available scientific research on infant mortality in the United States and across the world. There are studies showing artificial feeding's impact on overall infant death rates in both developing and undeveloped countries. While studies offering comparative death rates are not available for industrialized regions, there are numerous studies providing comparative occurrence rates for many illnesses and disorders in the United States and other industrialized nations. Many more reports are available extolling superior survival rates and decreased illness rates among breastfed infants, but only those with solid numbers are useful here. We can assemble the statistics from these studies to build a firm picture of the ratio of infant deaths for U.S. formula-fed babies against those who are breastfed.

 

The Relative Risks of Formula
It is clear that feeding infants artificial formula instead of breastfeeding increases their relative risk of death. A number of studies point to this fact. Table 1 shows figures from two studies measuring infant mortality risks during certain age ranges. A risk number of 3 in the chart represents three times the risk of infant death for infants who are artificially fed.

While the numbers in the charts reflect any amount of breastfeeding during the study period (and not necessarily exclusive breastfeeding), nearly all studies mention that during the first six months, exclusive breastfeeding produces much higher survival rates than partial breastfeeding. No studies refute this assertion. Figures for each age range listed here do not include children who died prior to reaching that age group. Figures reflect infants who received no breast milk or had weaned prior to reaching the reported age group versus those who received any breastfeeding through that age.

Table 1 clearly demonstrates that the disadvantages of formula are most devastating in the earliest months. Significant disadvantages for formula continue throughout the year-long study period.

Suggested Relative Risks for Infant Deaths
No Breastfeeding or Any Breastfeeding Ending Before Designated Age Ranges vs. Breastfeeding Through Designated Age Ranges
1,2

Country

Author

0 to 2 Months

3 to 5 Months

6 to 11 Months

Mexico

Palloni

13

6

3

Brazil , Pakistan and Philippines (pooled)

World Health
Organization

0 to 2 Months

2-3 Months

4-5 Months

6-8 Months

9-11 Months

 

6

4

2.5

2

1.5

A relative risk of 13 here means that a child who was not breastfed through the time period has thirteen times the risk of dying during his first year as a child who had received any breast milk through that period.

The studies cited in the next table compare no breastfeeding with 12 months of breastfeeding, each deriving a relative risk of death over the full first year.

Suggested Relative Risks for Infant Deaths
No Breastfeeding vs. Any Breastfeeding for 12 Months3-7

Country

Author

Current Infant Mortality Rate (IMR)

IMR During Period Study was Performed

Relative Risk To Formula-Fed Infants


United States

 

7

 

Number we wish to find

Malaysia

Habicht

19

30

> 2 *

Mexico (from Table 1)

Palloni

24

38

10 *


Philippines


Guilkey

28

31

> 5.5

China

Tu

27

36

> 3.0

Peru

Palloni

38

100

2.5

Brazil , Pakistan , and Philippines , pooled (from Table 1)

WHO

48 average

 

4.5 *

India

Srivastava

61

106

> 1.5

Infant Mortality Rates (IMR) are the number of infant deaths per 1,000 live births, from 0 to 12 months of age.
A relative risk of 5 here means that an infant who receives formula statistically faces five times the risk of dying as an infant who is partially or completely breastfed.
* These values are calculated from numbers provided in the studies, with averages weighted by percentages of total deaths occurring in each age range. More than two-thirds of deaths occur during the first month.

While the United States has a current infant mortality rate of 6.75 per thousand, many countries have rates approaching 100, with 16 of 225 reporting nations suffering well over 100 infant deaths for every 1,000 children born.8 The nations in the above table with lower infant mortality rates can thus be seen as somewhat comparable to the U.S.

Factors influencing high infant death rates include malnourished mothers, high numbers of births per mother with short spacing between births, poor weaning foods, the early use of cow's milk, inadequate medical attention and supplies, poor sanitation leading to high infection rates and a rapid spread of infectious disease, and limited education about methods of limiting infection and the spread of disease.

 

Why do U.S. Babies Die?
Below are the percentages and total numbers of U.S. infants who die from various leading causes, according to the 1999 National Vital Statistics Reports.9,10

Total U.S. births in 1999:

4,000,000

Total U.S. infant deaths in 1999:

28,000

 

20%

Congenital abnormalities (birth defects)

5,500

16%

Low birth weight and premature birth

4,500

10%

Sudden Infant Death Syndrome (SIDS)

2,700

8.5%

Complications during pregnancy and birth

2,400

6%

Respiratory distress: lung collapse, influenza, pneumonia

1,750

3%

Accidents (unintentional injuries)

850

2.5%

Bacterial sepsis (infections)

700

2.4%

Circulatory system diseases

650

1.4%

Necrotizing enterocolitis

400

1%

Intestinal inflammations (diarrhea)

300

0.3%

Meningitis

100

0.3%

Cancer

100

 

 

 

 

 

 



Numbers account for 70% of total infant deaths

So how does formula play into these deaths? Let's look at some of the common causes of infant death and see what current research has to say on the involvement of infant formula.

 

Sudden Infant Death Syndrome (SIDS)
Sudden Infant Death Syndrome (SIDS) accounts for a full 10% of U.S. infant deaths. Several studies performed in the United States and other industrialized nations reveal increased risks of SIDS among babies who receive formula instead of breast milk. In the table below, the 2002 Scandinavian study takes into account variables thought to have affected the 2000 U.S. study, finding even stronger risks associated with formula.

The most recent U.S. study (2003) takes advantage of the lessons from these earlier studies to raise confidence in its final results. Its finding of five times the risk of infant death from SIDS for formula-fed infants seems to be the most powerful statistic yet.

Studies Demonstrating Relative Risks of Infant Death from SIDS
Formula-Fed vs. Breastfed
11-17

Country

Author

Year of study publication

Relative risk for SIDS, formula-fed infants

United States

Hauck

2003

5

Scandinavia

Alm

2002

1.6 to 5.1

United States

McVea

2000

2

Germany

Schellscheidt

1997

7.7

England

Gilbert

1995

3.1

United States

Klonoff-Cohen

1995

2.7

New Zealand

Ford

1993

2

 

 

 

 






A relative risk of 5 here means that an infant who receives formula statistically faces five times the risk of dying from SIDS as an infant who is breastfed.

Heart, Circulatory and Respiratory Failure
Premature infants and those with circulatory abnormalities often display one or more warning signs of potential death, including inadequate oxygenation of the blood, apnea (episodes where breathing stops) and high blood pressure. Studies illustrate the dangers of formula for these infants. One study observed better body temperature and superior oxygenation in pre-term infants receiving breast milk. Formula-fed infants demonstrated many episodes of inadequate oxygenation and some apnea, both of which were not seen among the breastfed infants. A Scottish study found significantly better blood pressure among naturally fed infants.

Three U.S. studies are available examining feeding methods for infants with early circulatory problems. One study reported that more than half of infants with congenital heart disease lost oxygenation during bottle feedings, while none did so while breastfeeding. Another study also dealing with heart disease found infants' growth to be significantly inferior and their hospitalizations to be longer when they were fed formula. A third study of very low birth-weight infants found twice as many episodes of inadequate oxygenation among formula-fed infants as in those who received breast milk.

Heart and Circulatory Disease in Formula-Fed vs. Breastfed18-22

Country

Author

Year

Findings for formula-fed infants

Scotland

Wilson

1998

Higher blood pressure

Taiwan

Chen

2000

Apnea and many episodes of oxygen desaturation (none among breastfed infants)
Inferior body temperature regulation

USA

Bier

1993

Double the episodes of oxygen desaturation

USA

Combs

1993

Less growth; longer hospital stays

USA

Marino

1995

Oxygen desaturation during more than half of bottle feedings (none during breastfeeding)

 

 

 






Necrotizing Enterocolitis
Necrotizing enterocolitis is a severe intestinal inflammatory disorder that affects around 4% of low birth-weight babies and 1% of full-term infants. About one-third of low birth-weight infants and 20% of full-term infants who contract this disorder die. While necrotizing enterocolitis is reported to be responsible for 1.4% of infant deaths, many more unconfirmed cases are likely to be responsible for some portion of infant deaths reported as caused by prematurity.

In the United Kingdom , it was discovered that confirmed cases of necrotizing enterocolitis occurred in three times as many infants who received no breast milk as in those who received both breast milk and formula. For infants who exclusively received breast milk, necrotizing enterocolitis occurred six to 10 times less often than among wholly formula-fed infants.

 Necrotizing Enterocolitis23

Country

Author

Year

Relative risk of necrotizing enterocolitis, formula-fed infants

United Kingdom

Lucas

1990

6-10 times more often

 

 

Diarrhea
A World Health Organization (WHO) study revealed a risk of diarrhea for formula-fed babies in developing nations averaging more than six times that of breastfed babies. A summary article for industrialized nations demonstrated an average of triple the risk of diarrhea for formula-fed babies. The risk in China and Israel is reported as slightly less than triple (2.8); in Scotland , the risk is five-fold; and a doubled risk is measured in Canada .

While one study noted nearly twice the risk of developing diarrhea for artificially fed infants in Brazil , other studies have demonstrated that the risk of actually dying from diarrhea was an astounding 14 to 15 times greater. The latter studies demonstrated not only that the artificially fed infants suffer higher rates of illness, but also that the severity and duration of their illnesses are even greater when they do occur and result in proportionately more deaths. This same assertion is demonstrated in a study from India , where formula-fed infants suffer six times the death rate, once diarrhea occurs, as breastfed infants with diarrhea.

Four separate studies in the United States all deduce a doubled risk of diarrhea for formula-fed babies. The U.S. studies also reiterate the well-established factor of greater severity and extent of illness once diarrhea does occur among formula-fed babies. Death rates for formula-fed U.S. infants who get diarrhea may be three times higher or more than their breastfed contemporaries.

The table below collates the reported risks of diarrhea for formula-fed infants from many studies.

Diarrhea Risks for Formula-Fed vs. Breastfed24-40

Country

Author

Year


Relative risk of diarrheal illness (or death), formula-fed infants

Israel

Palti

1984

2.7 (during the first 5 months)

Brazil


Victora

1989

14 times the death rate

Scotland

Howie

1990

5 (compared with infants with 3 months of breastfeeding)

India

Sachdev

1991

6 times the death rate with diarrhea during the first 6 months

Canada

Beaudry

1995

1.9

Philippines

Yoon

1996

9 times the death rate

Mexico

Lopez-Alarcon

1997

4 to 6.3

Industrialized nations, pooled

Golding

1997

3 (gastroenteritis and diarrhea)

China

Fu

2000

2.8 (during the first 4 months)


6 developing nations

WHO

2000

6 (during the first 6 months)

Italy

Gianino

2002

3 (rotavirus, including increased severity)

Brazil

Escuder

2003

15 times the death rate (during the first 6 months)
2.2 times the death rate (from 4 to 11 months)

Brazil

Vieira

2003

1.8

USA

Dewey

1995

2

USA

Scariati

1997

1.8

USA

Wright

1998


2

USA

Raisler

1999

2 (during the first 6 months)

 

 

 

 

 

 

 






 

Respiratory Illnesses
Numerous studies document higher numbers of respiratory infections among formula-fed infants than among those who are breastfed. It is clear that respiratory infections are at least triple in the United States for formula-fed infants. The death rate is likely to be even higher, since some of these studies note that both the severity and extent of respiratory illnesses are considerably higher once they occur.

Respiratory Illness Risks for Formula-Fed vs. Breastfed41-50

Country

Author

Year

Relative risk of respiratory illness (or death), formula-fed infants

Israel

Palti

1984

3.7 (during the first 5 months)

Brazil

Victora

1987

3.6 times death

Italy

Pisacane

1994

4.5

Mexico

Lopez

1997

2 to 8.5 (during the first 4 months)
1.5 to 3 times as many days for each occurrence

Scotland

Wilson

1998

1.9 (during the first 4 months)

Brazil

Cesar

1999

17 times hospitalization for pneumonia

USA

Wright

1998

2 (bronchitis)
4 (pneumonia)

USA

Levine

1999

3.7 (pneumococcal disease, 2 to 11 months)

USA

Blaymore- Bier

2002

6 times as many days of upper respiratory infection (during the first month)

USA

Bachrach

2003

3.5 (severe respiratory tract illnesses)

 

 

 

 

 











Cancer
A joint study between the United States and Canada on neuroblastoma, a common childhood cancer, revealed a doubled risk for children who did not receive breast milk for more than one year. This study is consistent with several other childhood cancer studies in other nations, with results ranging from 1.45 to 4 times the risk for developing various common childhood cancers for formula-fed babies.

Childhood Cancer Risks for Formula-fed vs. Breastfed51-56

Country

Author

Year

Findings for formula feeding and cancer risks

China

Shu

1995

1.5 (leukemia and lymphoma)

UAE

Bener

2001

2.8 (leukemia and lymphomas for no or less than 6 months breastfed versus longer breastfeeding)

France

Perrillat

2002

2 (leukemia for breastfeeding over 6 months)

U.S. & Canada

Daniels

2002

2 (neuroblastoma)

 

 

 

 

Low Birth-Weight and Pre-term Birth
Representing 16% of U.S. infant mortality totals, premature birth and low birth-weight are the second leading diagnoses on death certificates of U.S. infants. While prematurity may lay the foundation for difficulties in tiny infants, the factors that actually take their lives include infection, respiratory distress, unconfirmed necrotizing enterocolitis, circulatory deficiency and diarrhea. These diagnoses are often detectable only with a biopsy, so the listed cause in these cases is often simply prematurity. One study that performed autopsies on a group of extremely low birth-weight infants who had not survived found that infection was the actual primary cause of death for half of the infants. Prematurity was the cause of death predominantly for infants who weighed less than one pound.

Preemies in India who received only preemie formula were found to develop more than twice as many infections as those who received some human milk. Another Indian study on high-risk newborns found that those receiving human milk plus formula suffered twice the infection rate of those receiving only pasteurized human milk and triple the rate of those receiving only raw human milk. A Columbian study found a nearly doubled death rate for low birth-weight infants who were partially or completely formula fed. And a Malaysian study found a huge difference in total infant survival among extremely low birth-weight babies who received expressed breast milk as opposed to those who did not.

A U.S. study performed at George Washington University Hospital found 2.5 times the number of infections among formula-fed infants in the intensive care unit than among those receiving human milk. Another study at Georgetown University Medical Center also found more than double the number of infections in very low birth-weight infants not receiving human milk. A San Diego study found twice as many infections in pre-term, formula-fed infants compared with infants who received human milk.

As shown in many other studies, the extent and severity of infection among pre-term and low birth-weight infants are generally greater in formula-fed infants as well. One study gives a solid example for preemies, finding respiratory infections among U.S. formula-fed preemies to run six times as many days as those in their breastfed counterparts.

Pre-term Infant Illness and Death Rates57-64


Country

Author

Year

Relative risk for illness or death, formula-fed pre-term and low birth-weight infants

India

Narayanan

1980

2.25 times the infections for no breast milk as opposed to some

India

Narayanan

1984

2 times the infections for formula plus pasteurized breast milk as pasteurized breast milk alone3 times the infections as raw breast milk alone

Malaysia

Boo

2000

Many times the death rate for no breast milk

Columbia

Charpak

2001


2 times the death rate for any amount of formula as for exclusive breastfeeding

USA

el-Mohandes

1997

2.5 times the infections

USA

Hylander

1998

2 times the infections

USA

Schanler

2001

2 times the infections

USA

Blaymore-Bier

2002

6 times the duration of upper respiratory infections

 

 

 

 

 

 

 

 

 


Exclusive feeding of raw breast milk is not always an option for premature infants, although it is common in some hospitals with excellent support. Sometimes, less-effective pasteurized breast milk is used and often fortifiers are added. Several studies show decreased survival for infants fed milk with added fortifiers as opposed to those fed unfortified milk,65-68 but the picture is complex and the choices of fortifiers vary greatly.

And finally, it is worth noting that the eye damage that can occur in very low birth-weight infants, retinopathy of prematurity, occurs only half as often in infants who receive some breast milk.69 Even a disorder as apparently unrelated to feeding methods as inguinal hernia has been discovered to occur twice as often in artificially fed infants and even more frequently when compared with infants who are exclusively breastfed.70

 

Congenital Abnormalities
Twenty percent of U.S. infant deaths are attributed to birth defects. The most common potentially lethal birth defects include heart disorders, various chromosomal or genetic defects and underdeveloped lungs. In terms of infant formula's impact, we have the least amount of statistical information in this category. However, many factors suggest that formula-fed infants with congenital abnormalities have smaller chances of survival than their breastfed counterparts.

While death certificates often list the initial abnormality as the cause of death, infection is actually the final factor in many of these deaths. We have already seen how drastically infection rates and deaths are reduced by breastfeeding. It is clear that the youngest and weakest infants are the ones who are most strongly endangered by infant formula's inadequacies.

Studies suggest that formula-fed infants suffer inferior blood oxygenation and higher blood pressure as well as more episodes of apnea (cessation of breathing for a short time) than their breastfed counterparts. While no studies compare the actual survival of such infants in the United States , it is obvious that some proportion of babies with congenital heart abnormalities is being seriously disadvantaged by formula feedings. Artificially fed infants with heart defects requiring surgery are less likely to live until their surgery and less likely to recover from surgery's challenges.

A wide variety of common birth defects has been shown to have better survival rates among breastfed infants, although the actual figures are not available. Most birth defects have not been specifically studied in this regard. The background information, nonetheless, is striking.

For example, infants born with phenylketonuria (PKU), a defect in handling a certain protein in the diet, need specialized supplementation to breast milk in order to prevent mental retardation and other difficulties. Yet a study demonstrated that infants who had been breastfed before being diagnosed with PKU fared far better than those who had been fed on formula.71 The greatest complications for infants with cystic fibrosis are lung infection, decreased oxygenation and malnutrition — all of which are recognized to be complicated by formula feeding.72 The negative impact of formula on neurological development has been demonstrated in healthy infants.73-76 One study that quantified the effect reported double the amount of neurological "non-normality" in formula-fed infants.77 It is reasonable to assume that neurological damage or problems stemming from birth disorders can be exacerbated by artificial feeding.

Clearly, feeding choice may have a significant impact on the survival of infants born with various defects, although there is not enough information available to render an actual ratio of survival.

 

Complications of Pregnancy and Birth
Complications of pregnancy and birth produce a wide range of injuries and problems for babies. Some certainly pose no hope of survival. Infection, insufficient neurological recovery and inadequate oxygenation lead to many infant deaths. Artificial feeding certainly has some degree of impact on mortality in these cases. Based on a lack of further detailed evidence, we will apply a very modest number to figures for increased risk of death for formula-fed infants in this category.

 

Accidents
It seems logical that accidents happen equally among artificially and naturally fed infants. Figures bear this out. One paper actually measured accidental injuries between breast- and formula-fed infants, finding an equal number in both.78

 

Examining the Numbers
So now we are left to examine artificial feeding's actual impact on all American babies. First, we note that there should be a relationship dictating that if rates for a certain disease are doubled by formula feeding, for instance, then death rates for that disease may also be somewhere in the neighborhood of doubled when compared with rates for breastfed infants. In fact, the evidence suggests that the death rates would be even higher. While formula feeding may result in twice as many episodes of a certain illness, a great number of studies demonstrate that each of these episodes are also longer and more severe. This would suggest that the rate of death among artificially fed infants from various causes would actually be higher than the rates that the various illnesses occur.

The reported percentages of U.S. infants dying from each cause include a certain number of infants who were breastfed and a portion who were formula-fed. Because formula feeding's impact is much more or less influential in some disorders than others, we need to weigh each category accordingly. (This exercise will account for the assumption that a lower proportion of infants who died from congenital abnormalities, for instance, were formula-fed infants than the proportion who died from SIDS.) Because two-thirds of all infants die in the first month, and because exclusive breastfeeding runs about 50% during the first month, this number can be used in the calculations to help weigh the greater or lesser impact of breastfeeding for each cause.

2001 U.S. Breastfeeding Rates79,80

Study

Hospital Initiation

4 Months

6 Months

12 Months

 

Any BF

Exclusive

Any BF

Exclusive

Any BF

Exclusive

Any

Ross/Abbott Labs

69.5%

46.2%

 

 

32.5%

17.2%

 

National Immunization Survey

65.1%

59%

35%

24%

27%

7.9%

12.3%

 

 

 


An overall risk rate of infant death for formula-fed infants has been selected conservatively based on the available information presented in this paper for each cause of death in the table below. Assuming that 50% of the total infants born were breastfed, we can calculate formula-fed and breastfed infant death rates and totals for each cause.

Because one-third of the deaths actually occurred as the percentage of infants breastfeeding was dropping to a much smaller number, the use of 50% throughout the calculations keeps the resultant finding very conservative. Although the literature reiterates time and again how the extent, severity and frequency of disease is greater in formula-fed infants, I have only taken this factor into account in an extremely conservative manner in instances where the literature provides solid numerical examples. In other instances where this aspect is not clearly demonstrated, I have not used this factor at all. Again, this effort keeps the final quotient conservative. Finally, the ratios from many studies used are for full formula feeding versus any amount of breastfeeding. Some of these ratios would be much higher if formula feeding were compared to exclusive breastfeeding. This factor again keeps our final conclusion conservative.

 

Here's the Math
There are 4,000,000 births annual births in the United States . Using 50% as the number of infants who have actually been breastfed, the number of infants breastfed (B) equals 2,000,000. The number of formula-fed (F) infants also equals 2,000,000.

B = F = 2,000,000

R = Infant Mortality Rate (IMR) for each cause

RB = IMR for breastfed


RF = IMR for formula fed

Rel = Estimated Relative Risk for formula feeding versus breastfeeding, for each cause

 

RFF + RBB = Total Number of Deaths for that cause = TND

 

RF = Rel x RB

 

RF x 2,000,000 + RB x 2,000,000 = TND

 

Rel x RB x 2,000,000 + RB x 2,000,000 = TND

 

RB = __________TND___________

 

Rel x 2,000,000 + 2,000,000

 

RB x 4,000,000 = Number Deaths if all B

 

 

 

 

 

 

 

 

 



Let's apply this formula to congenital abnormalities. Clearly, feeding's impact in this category could be significant, but there is not enough solid statistical evidence to say for sure. If we modestly assume a 50% higher death rate for the 50% of formula-fed infants, the number of breastfed infants who died would be 2,200. The number of formula-fed who died would be 3,300. If all of the infants had actually been breastfed, then the total number of deaths would be 4,400 — a savings of 1,100 lives.

The relative risk for formula feeding in other categories was much more clearly defined by the studies. Conservative but appropriate rates were selected, as seen in the table below.

Calculating Formula's Final Impact

Cause of death

Actual U.S. infant deaths (1999)

Relative risk for formula-fed infants

Estimated
IMR for breastfed babies

Deaths if all were breastfed

Deaths if all were formula-fed

Lives saved if all were breastfed

Congenital abnormality

 5500

 1.5

 1.1

 4400

 6600

 1100

Prematurity

 4500

 2.5

 .643

 2570

 6430

 1930

SIDS

 2700

 4

  .27

 1080

 4320

 1620

Complications of pregnancy & birth

 2400

1.25

 .533

2135

2670

270

Respiratory distress & infections

1750

4

.175

700

2800

1050

Accidents

850

1

.213

850

850

0

Bacterial infection

700

3

.087

350

1050

350

Circulatory problems

650

1.5

.13

520

780

130

Necrotizing enterocolitis

400

8

.022

90

710

310

Diarrhea

300

2.5

.043

170

430

130

Meningitis

100

3

.014

55

170

45

Cancer

100

2

.02

80

160

20

 

 

 

 

 

 

 

SUBTOTALS

19950

2.075

3.25

13000

26970

6955

All other

8050

2

1.6

6440

12880

1610

TOTALS

28000

2

4.7

18665

37335
IMR 9.4

9335

Infant Mortality Rates (IMR) are the number of infant deaths per 1,000 live births, from 0 to 12 months of age.

Based on the current U.S. infant death rate of 6.75 and an average breastfeeding rate of 50%, the American infant mortality rate would climb to 9.4 if all infants were formula-fed and would drop to 4.7 if all were breastfed. Twenty-two nations with high rates of breastfeeding have infant mortality rates below 5, while the U.S. ranks higher in infant death than 41 other nations.81 Clearly, lower rates for the United States are a possibility.

 

The Ugly Truth About Formula
From the above statistics, we see that formula feeding costs American babies more than four additional lives per thousand. The final relative risk for formula feeding comes out to 2 — that's double the risk of death for American infants who are fed with formula, compared with babies who are fed naturally.

A multitude of studies demonstrate that when breastfeeding is accompanied by formula supplementation, illness and death rates are much closer to those of babies who are fully formula-fed. Studies also reveal conclusively that the longer breastfeeding lasts, the greater the measurable difference in illness and death rates.

 

Answering the Detractors
Criticisms are often spread about studies that find increased illness and death rates associated with formula feeding. For just this reason, each later study aggressively attempts to take into account any factors that have been purported as distorting previous study outcomes. These research papers address as many aspects as possible, from maternal education, to smoking, to income level, to day care usage and many more possibilities. The results continue to reveal the risks of formula feeding.

It's commonly said that formula feeding does not risk lives in industrialized nations where education and medical advances prevent increased deaths. The evidence is quite to the contrary. Some insist that the blame for the United States ' relatively high infant death rate lies with underprivileged communities. Again, it has been shown that elevated death rates among U.S. blacks cannot be attributed to poverty. Hispanic Americans rank similarly to African-American populations for socio-economic factors, but they match non-Hispanic whites in their lower infant mortality rates. The difference is not socio-economic; rather, it's in rates of formula use versus breastfeeding.82-84

A New York study sought to establish the connection between education, income and infant survival. It concluded strongly that the number of illnesses is increased by two to three times in formula-fed babies regardless of socioeconomic status or level of parental education.85 A later study in Israel confirmed the effects of formula feeding across all classes and education levels.86 The most recent analysis of this issue, again performed in the United States, reiterated that higher illness rates among formula-fed or formula-supplemented infants "did not differ among income groups."87

 

And Beyond the First Year
While the extent of breast milk's health protection declines with age, a great number of studies demonstrate the continued survival advantage of breastfeeding through the second year and beyond. A World Health Organization study of less-developed countries found a doubled risk of death in the second year of life for those weaned prematurely or never receiving breast milk.88 A study in The Netherlands found a strong correlation between the extent of breastfeeding and the number of illnesses in children. Significant protection from breastfeeding was noted during the first three years of life.89 Other studies show a sizeable increase in illnesses throughout all of childhood for those who were never breastfed or prematurely weaned.90-92 In fact, an increased risk of death throughout life has been well documented for people who were formula-fed. Higher blood pressure, more heart disease, obesity, diabetes and artery disease, a nearly doubled rate of Crohn's disease and tripled rates of celiac disease have all been associated with early formula feeding.93-105

 

What Your Doctor Doesn't Tell You
Pediatricians spend much time frightening parents with 1 in 100,000 risks from vaccine-preventable diseases when parents question the utility and safety of vaccines. "Would you want to risk the life of your child?" they demand. Yet these very same professionals offer formula samples with the other hand — when the magnitude of health risks associated with the use of formula is 500 times greater.

Parenting is all about making choices and weighing risks and benefits. Many parents need to make the riskier choice of formula feeding in order to balance other factors that benefit the family. Yet some parents who have lost their children, possibly based on pediatric advice condoning or encouraging formula-feeding, would surely wish that they had been informed of the very real risks related to using formula.

 

 

ENDNOTES
1. Palloni et al., "The effects of breast-feeding and the pace of childbearing on early childhood mortality in Mexico ," Bulletin of the Pan American Health Organization ( Mexico ) 28, no.2 (Jun 1994): 93-111.

2. WHO Collaborative Study Team on the Role of Breastfeeding on the Prevention of Infant Mortality, "Effect of breastfeeding on infant and child mortality due to infectious diseases in less developed countries: a pooled analysis," Lancet 355, no. 9202 (Feb 2000): 451-5.

3. J.P. Habicht et al., "Does breastfeeding really save lives, or are apparent benefits due to biases?" American Journal of Epidemiolofy 123, no. 2 (Feb 1986): 279-90.

4. D.K. Guilkey and R.T. Riphahn, "The determinants of child mortality in the Phillipines: estimation of a structural model," Journal of Development Economics (US and Germany ) 56, no. 2 (Aug 1998): 281-305.

5. P. Tu, "The effects of breastfeeding and birth spacing on child survival in China ," Studies in Family Planning ( China ) 20, no. 6 (Nov.-Dec. 1989): 332-342.

6. Palloni and M. Tienda, "The effects of breastfeeding and pace of childbearing on mortality at early ages," Demography (US) 23, no. 1 (Feb 1986): 31-52.

7. S.P. Srivastava et al., "Mortality patterns in breast versus artificially fed term babies in early infancy: a longitudinal study," Indian Peadrics ( India ) 31, no. 11 (Nov 1994): 1393-6.

8. The World Fact Book, http://www.odci.gov/cia/publications/factbook/rankorder/2091rank.html

9. National Vital Statistics Report, 49, no. 11 (Oct 12, 2001): 1-12.

10. National Vital Statistics Report, 50, no. 16 (Sep 16, 2002): 1-12.

11. F.R. Hauck et al., "Sleep environment and the risk of Sudden Infant Death Syndrome in an urban population: the Chicago infant mortality study," Pediatrics (US) 111, no. 5 (May 2003): 1207-1214.

12. B. Alm et al., "Breastfeeding and the sudden infant death syndrome in Scandinavia, 1992-1995," Archives of Disease in Childhood (Sweden) 86 (2002:400-402.

13. K.L. McVea et al., "The role of breastfeeding in sudden infant death syndrome," Journal of Human Lactation (US) 16, no. 1 (Feb 2000): 13-20.

14. J. Schellscheidt et al., "Epidemiological features of sudden infant death after a German intervention campaign in 1992," Eur J Pediatr ( Germany ) 156, no. 8 (Aug 1997): 655-60.

15. R.E. Gilbert, "Bottle feeding and the sudden infant death syndrome," British Medical Journal ( England ) 310, no. 6972 (Jan 14, 1995): 88-90.

16. H.S. Klonoff-Cohen et al., "The effect of passive smoking and tobacco exposure through breast milk on sudden infant death syndrome," JAMA (US) 273, no. 10 (Mar 1995): 795-8.

17. R.P. Ford et al., "Breastfeeding and the risk of sudden infant death syndrome," International Journal of Epidemiology ( New Zealand ) 22, no. 5 (Oct. 1993): 885-90.

18. A.C. Wilson et al., "Relation of infant diet to childhood health: seven year follow up of cohort of children in Dundee infant feeding study," BMJ ( Scotland ) 316, no. 7124 (Jan 1998): 21-5.

19. C.H. Chen et al., "The effect of breast- and bottle-feeding on oxygen saturation and body temperature in preterm infants," Journal of Human Lactation ( Taiwan ) 16, no. 1 (Feb 2000): 21-7.

20. J.B. Bier et al., "Breast-feeding of very low birth weight infants," Journal of Pediatrics ( Rhode Island , USA ) 123, no. 5 (Nov 1993): 773-8.

21. V.L. Combs and B.L. Marina, "A comparison of growth patterns in breast and bottle-fed infants with congenital heart disease," Pediatric Nursing (USA) 19, no. 2 (Mar-Apr 1993):175-9.

22. B.L. Marino et al., "Oxygen saturations during breast and bottle feedings in infants with congenital heart disease," Journal of Pediatric Nursing (USA) 10, no. 6 (Dec 1995): 360-4.

23. A. Lucas and T.J. Cole, "Breast milk and neonatal necrotising enterocolitis," Lancet ( UK ) 336, no. 8730 (Dec 22-29, 1990): 1519-23.

24. H. Palti et al., "Episodes of illness in breast-fed and bottle-fed infants in Jerusalem ," Israel Journal of Medical Science ( Israel ) 20, no. 5 (May 1984): 395-9.

25. C.G. Victora et al., "Infant feeding and deaths due to diarrhea. A case-control study," American Journal of Epidemiology ( Brazil ) 129, no. 5 (May 1989): 1032-41

26. P.W. Howie et al., "Protective effect of breast feeding against infection," British Medical Journal ( Scotland ) 300, no. 6716 (Jan 6, 1990): 11-6.

27. H.P. Sachdev et al., "Does breastfeeding influence mortality in children hospitalized with diarrhoea?" Journal of Tropical Pediatrics ( India ) 37, no. 6 (Dec 1991): 275-9.

28. M. Beaudry et al., "Relation between infant feeding and infections during the first six months of life," Journal of Pediatrics ( Canada ) 126, no. 2 (Feb 1995): 191-7.

29. P.W. Yoon, "Effect of not breastfeeding on the risk of diarrheal and respiratory mortality in children under 2 years of age in Metro Cebu, The Philippines," American Journal of Epidemiology ( Philippines ) 143, no. 11 (Jun 1996): 1142-8.

30. M. Lopez-Alarcon et al., "Breast-feeding lowers the frequency and duration of acute respiratory infection and diarrhea in infants under six months of age," J Nutr ( Mexico ) 127, no. 3 (Mar 1997): 436-43.

31. J. Golding et al, "Gastroenteritis, diarrhoea and breast feeding," Early Human Development ( England